A 803467

Catalog No. A11234

A 803467是NaV1.8通道的选择性阻滞剂（hNaV1.8，hNaV1.3，hNaV1.7，hNaV1.5和hNaV1.2通道的IC50值分别为8、2450、6740、7340和7380 nM）。

Technical details

Catalog Num	A11234
M. Wt	357.8
Formula	C19H16ClNO4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	944261-79-4
Synonyms	A-803467, A803467
SMILES	COC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl)OC

Biological Activity

A 803467是NaV1.8通道的选择性阻滞剂（hNaV1.8，hNaV1.3，hNaV1.7，hNaV1.5和hNaV1.2通道的IC50值分别为8、2450、6740、7340和7380 nM）。

Targets

Na(V1.8) channel
8 nM

Solubility *

In vitro (25°C)	DMSO	64 mg/mL (178.87 mM)
	Water	Insoluble
	Ethanol	10 mg/mL (27.95 mM)
In vivo	2% DMSO+corn oil	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.95 mL	139.74 mL	279.49 mL
0.5 mM	5.59 mL	27.95 mL	55.9 mL
1 mM	2.79 mL	13.97 mL	27.95 mL
5 mM	0.56 mL	2.79 mL	5.59 mL

*The above data is based on the productmolecular weight 357.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.