Alvimopan (ADL 8-2698)

Catalog No. A11292

Alvimopan (ADL 8-2698)表现为外周作用的opioid拮抗剂，Alvimopan竞争性结合胃肠道中的mu-opioid receptor。

Technical details

Catalog Num	A11292
M. Wt	424.5
Formula	C25H32N2O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	156053-89-3
Synonyms	ADL 8-2698, Entereg, LY 246736
SMILES	C[C@H]1CN(CC[C@@]1(C)C2=CC(=CC=C2)O)C[C@H](CC3=CC=CC=C3)C(=O)NCC(=O)O

Biological Activity

Alvimopan (ADL 8-2698)表现为外周作用的opioid拮抗剂，Alvimopan竞争性结合胃肠道中的mu-opioid receptor。

Solubility *

In vitro	DMSO	79 mg/mL (186.09 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.56 mL	117.79 mL	235.57 mL
0.5 mM	4.71 mL	23.56 mL	47.11 mL
1 mM	2.36 mL	11.78 mL	23.56 mL
5 mM	0.47 mL	2.36 mL	4.71 mL

*The above data is based on the productmolecular weight 424.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Alvimopan (ADL 8-2698)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions