AS 602801 (Bentamapimod)

Catalog No. A11296

AS 602801 (Bentamapimod)是一种新型口服活性Jun激酶抑制剂。

Product Citations

Shuai Zhang, .et al. AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes, J Cell Mol Med, 2021, Apr;25(8):4062-4072 PMID: 33609076
Kuramoto K, .et al. AS602801, an Anti-Cancer Stem Cell Drug Candidate, Suppresses Gap-junction Communication Between Lung Cancer Stem Cells and Astrocytes, Anticancer Res, 2018, Sep;38(9):5093-5099 PMID: 30194154

Technical details

Catalog Num	A11296
M. Wt	547.6
Formula	C25H23N5O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	848344-36-5
Synonyms	AS-602801, AS602801
SMILES	C1COCCN1CC2=CC=C(C=C2)COC3=NC=CC(=N3)C(C#N)C4=NC5=CC=CC=C5S4

Biological Activity

AS 602801 (Bentamapimod)是一种新型口服活性Jun激酶抑制剂。

Solubility *

In vitro	DMSO	21 mg/mL (45.89 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.26 mL	91.31 mL	182.62 mL
0.5 mM	3.65 mL	18.26 mL	36.52 mL
1 mM	1.83 mL	9.13 mL	18.26 mL
5 mM	0.37 mL	1.83 mL	3.65 mL

*The above data is based on the productmolecular weight 547.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.