BG45

Catalog No. A11361

BG45是一种HDAC I类抑制剂，对HDAC3具有选择性（IC50 = 289 nM）。它抑制HDAC1，HDAC2和HDAC6的效力大大降低（IC50分别为2、2和> 20μM）。

Technical details

Catalog Num	A11361
M. Wt	214.22
Formula	C11H10N4O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	926259-99-6
Synonyms	BG 45, BG-45
SMILES	NC1=CC=CC=C1/N=C(O)/C2=CN=CC=N2

Biological Activity

BG45是一种HDAC I类抑制剂，对HDAC3具有选择性（IC50 = 289 nM）。它抑制HDAC1，HDAC2和HDAC6的效力大大降低（IC50分别为2、2和> 20μM）。

Targets

HDAC3	HDAC1	HDAC2	HDAC6
289 nM	2 μM	2.2 μM	>20 μM

Solubility *

In vitro	DMSO	40 mg/mL (186.72 mM)
	Water	Insoluble
	Ethanol	Warmed: 2 mg/mL (9.33 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	46.68 mL	233.4 mL	466.81 mL
0.5 mM	9.34 mL	46.68 mL	93.36 mL
1 mM	4.67 mL	23.34 mL	46.68 mL
5 mM	0.93 mL	4.67 mL	9.34 mL

*The above data is based on the productmolecular weight 214.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.