LY2608204

Catalog No. A11406

LY2608204是治疗2型糖尿病的有效药物。是葡萄糖激酶（GK）活化剂，EC50为42 nM。

Technical details

Catalog Num	A11406
M. Wt	559.8
Formula	C28H37N3O3S3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1234703-40-2
Synonyms	LY-2608204
SMILES	C1CCC(CC1)[C@@H]2C[C@@]2(C3=CC=C(C=C3)S(=O)(=O)C4CC4)C(=O)NC5=NC=C(S5)SCCN6CCCC6

Biological Activity

LY2608204是治疗2型糖尿病的有效药物。是葡萄糖激酶（GK）活化剂，EC50为42 nM。

Targets

glucokinase
42 nM(EC50)

Solubility *

In vitro (25°C)	DMSO	95 mg/mL (169.69 mM)
	Water	Insoluble
	Ethanol	30 mg/mL (53.59 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.86 mL	89.32 mL	178.64 mL
0.5 mM	3.57 mL	17.86 mL	35.73 mL
1 mM	1.79 mL	8.93 mL	17.86 mL
5 mM	0.36 mL	1.79 mL	3.57 mL

*The above data is based on the productmolecular weight 559.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.