Etravirine ( R165335, TMC125)

Catalog No. A11417

Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

Technical details

Catalog Num	A11417
M. Wt	435.28
Formula	C20H15BrN6O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	269055-15-4
Synonyms	R-165335; R 165335; TMC 125;TMC-125
SMILES	N#CC1=CC(C)=C(C(C)=C1)OC2=NC(NC3=CC=C(C=C3)C#N)=NC(N)=C2Br

Biological Activity

Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

Solubility *

In vitro	DMSO	40 mg/mL (91.89 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.97 mL	114.87 mL	229.74 mL
0.5 mM	4.59 mL	22.97 mL	45.95 mL
1 mM	2.3 mL	11.49 mL	22.97 mL
5 mM	0.46 mL	2.3 mL	4.59 mL

*The above data is based on the productmolecular weight 435.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Etravirine ( R165335, TMC125)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions