GSK-923295

Catalog No. A11435

GSK-923295是有丝分裂驱动蛋白着丝粒相关蛋白E（CENP-E）的小分子抑制剂。

Technical details

Catalog Num	A11435
M. Wt	592.13
Formula	C32H38ClN5O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1088965-37-0
Synonyms	GSK923295, GSK 923295
SMILES	C[C@@H](C1=CC=CN2C1=NC(=C2)C3=CC=C(C=C3)C[C@@H](CNC(=O)CN(C)C)NC(=O)C4=CC(=C(C=C4)OC(C)C)Cl)O

Biological Activity

GSK-923295是有丝分裂驱动蛋白着丝粒相关蛋白E（CENP-E）的小分子抑制剂。

Targets

CENP-E
3.2 nM(Ki)

Solubility *

In vitro	DMSO	90 mg/mL (151.99 mM)
	Water	Insoluble
	Ethanol	90 mg/mL (151.99 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.89 mL	84.44 mL	168.88 mL
0.5 mM	3.38 mL	16.89 mL	33.78 mL
1 mM	1.69 mL	8.44 mL	16.89 mL
5 mM	0.34 mL	1.69 mL	3.38 mL

*The above data is based on the productmolecular weight 592.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.