KN-62

Catalog No. A11473

KN-62是一种有效，选择性的钙调蛋白依赖性蛋白激酶 II (CaMK-II)抑制剂。

Technical details

Catalog Num	A11473
M. Wt	721.8
Formula	C38H35N5O6S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	127191-97-3
Synonyms
SMILES	CN([C@@H](CC1=CC=C(C=C1)OS(=O)(=O)C2=CC=CC3=C2C=CN=C3)C(=O)N4CCN(CC4)C5=CC=CC=C5)S(=O)(=O)C6=CC=CC7=C6C=CN=C7

Biological Activity

KN-62是一种有效，选择性的钙调蛋白依赖性蛋白激酶 II (CaMK-II)抑制剂。

Targets

CaMKII
0.9 μM(Ki)

Solubility *

In vitro	DMSO	96 mg/mL (132.99 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.85 mL	69.27 mL	138.54 mL
0.5 mM	2.77 mL	13.85 mL	27.71 mL
1 mM	1.39 mL	6.93 mL	13.85 mL
5 mM	0.28 mL	1.39 mL	2.77 mL

*The above data is based on the productmolecular weight 721.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.