Ko-143

Catalog No. A11475

ko 143是有效的选择性乳腺癌耐药蛋白多药转运蛋白(BCRP)抑制剂，EC90值为26 nM。

Technical details

Catalog Num	A11475
M. Wt	469.59
Formula	C26H35N3O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	461054-93-3
Synonyms	Ko 143,Ko143
SMILES	O=C1N2[C@@H](CC(C)C)C(NC3=C4C=CC(OC)=C3)=C4C[C@@H]2C(N[C@@H]1CCC(OC(C)(C)C)=O)=O

Biological Activity

ko 143是有效的选择性乳腺癌耐药蛋白多药转运蛋白(BCRP)抑制剂，EC90值为26 nM。

Solubility *

In vitro	DMSO	89 mg/mL (189.53 mM)
	Water	Insoluble
	Ethanol	89 mg/mL (189.53 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.3 mL	106.48 mL	212.95 mL
0.5 mM	4.26 mL	21.3 mL	42.59 mL
1 mM	2.13 mL	10.65 mL	21.3 mL
5 mM	0.43 mL	2.13 mL	4.26 mL

*The above data is based on the productmolecular weight 469.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Ko-143

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions