Nelfinavir
Catalog No. A11504
Nelfinavir是一种有效的口服生物可利用的人类免疫缺陷病毒HIV-1蛋白酶抑制剂(Ki=2 nM ),广泛用于与HIV逆转录酶抑制剂联合治疗HIV感染。
- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- Yang PM, .et al. p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma, Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
| Catalog Num | A11504 |
|---|---|
| M. Wt | 567.78 |
| Formula | C32H45N3O4S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 159989-64-7 |
| Synonyms | Viracept, AG 1341, AG-1341, AG1341 |
| SMILES | CC1=C(C=CC=C1O)C(=O)NC(CSC2=CC=CC=C2)C(CN3CC4CCCCC4CC3C(=O)NC(C)(C)C)O |
Nelfinavir是一种有效的口服生物可利用的人类免疫缺陷病毒HIV-1蛋白酶抑制剂(Ki=2 nM ),广泛用于与HIV逆转录酶抑制剂联合治疗HIV感染。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.61 mL | 88.06 mL | 176.12 mL |
| 0.5 mM | 3.52 mL | 17.61 mL | 35.22 mL |
| 1 mM | 1.76 mL | 8.81 mL | 17.61 mL |
| 5 mM | 0.35 mL | 1.76 mL | 3.52 mL |
*The above data is based on the productmolecular weight 567.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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