Regorafenib Hydrochloride
Catalog No. A11546
Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
| Catalog Num | A11546 |
|---|---|
| M. Wt | 519.28 |
| Formula | C21H16Cl2F4N4O3 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 835621-07-3 |
| Synonyms | BAY73-4506 hydrochloride |
| SMILES | ClC1=C(C(F)(F)F)C=C(NC(NC2=C(F)C=C(OC3=CC=NC(C(NC)=O)=C3)C=C2)=O)C=C1.Cl |
Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.26 mL | 96.29 mL | 192.57 mL |
| 0.5 mM | 3.85 mL | 19.26 mL | 38.51 mL |
| 1 mM | 1.93 mL | 9.63 mL | 19.26 mL |
| 5 mM | 0.39 mL | 1.93 mL | 3.85 mL |
*The above data is based on the productmolecular weight 519.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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