Riociguat (BAY 63-2521)

Catalog No. A11549

Riociguat (BAY 63-2521)是可溶性鸟苷酸环化酶(sGC)的刺激物。

Technical details

Catalog Num	A11549
M. Wt	422.42
Formula	C20H19FN8O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	625115-55-1
Synonyms	BAY 63-2521; BAY 632521
SMILES	CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC

Biological Activity

Riociguat (BAY 63-2521)是可溶性鸟苷酸环化酶(sGC)的刺激物。

Targets

guanylate cyclase

Solubility *

In vitro	DMSO	76 mg/mL (179.91 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.67 mL	118.37 mL	236.73 mL
0.5 mM	4.73 mL	23.67 mL	47.35 mL
1 mM	2.37 mL	11.84 mL	23.67 mL
5 mM	0.47 mL	2.37 mL	4.73 mL

*The above data is based on the productmolecular weight 422.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.