Vincristine

Catalog No. A11617

Vincristine是通过与微管蛋白结合的微管聚合抑制剂,IC50为32μM。
  • Li-Li Li, .et al. Resonance energy transfer sensitises and monitors in situ switching of LOV2-based optogenetic actuators, Nat Commun, 2020, Oct 9;11(1):5107 PMID: 33037199
Catalog Num A11617
M. Wt 824.96
Formula C46H56N4O10
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 57-22-7
Synonyms 0
SMILES CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
Vincristine是通过与微管蛋白结合的微管聚合抑制剂,IC50为32μM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.12 mL 60.61 mL 121.22 mL
0.5 mM 2.42 mL 12.12 mL 24.24 mL
1 mM 1.21 mL 6.06 mL 12.12 mL
5 mM 0.24 mL 1.21 mL 2.42 mL

*The above data is based on the productmolecular weight 824.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.