Azilsartan (TAK-536)

Catalog No. A11775

Azilsartan (TAK-536)是一种用于治疗高血压的血管紧张素II受体拮抗剂。

Technical details

Catalog Num	A11775
M. Wt	456.5
Formula	C25H20N4O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	147403-03-0
Synonyms	TAK536
SMILES	CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)O

Biological Activity

Azilsartan (TAK-536)是一种用于治疗高血压的血管紧张素II受体拮抗剂。

Targets

AT1 receptor
2.6 nM

Solubility *

In vitro (25°C)	DMSO	78 mg/mL (170.88 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.91 mL	109.53 mL	219.06 mL
0.5 mM	4.38 mL	21.91 mL	43.81 mL
1 mM	2.19 mL	10.95 mL	21.91 mL
5 mM	0.44 mL	2.19 mL	4.38 mL

*The above data is based on the productmolecular weight 456.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.