GSK2636771

Catalog No. A11784

GSK2636771是一种有效的口服生物可用的PI3Kβ选择性抑制剂。

Product Citations

Pridham KJ, .et al. PIK3CB/p110β is a selective survival factor for glioblastoma, Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844

Technical details

Catalog Num	A11784
M. Wt	433.4
Formula	C22H22F3N3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1372540-25-4
Synonyms	GSK 2636771
SMILES	CC1=C(C=CC=C1C(F)(F)F)CN2C(=NC3=C2C=C(C=C3C(=O)O)N4CCOCC4)C

Biological Activity

GSK2636771是一种有效的口服生物可用的PI3Kβ选择性抑制剂。

Targets

PI3Kβ

Solubility *

In vitro	DMSO	28 mg/mL (64.6 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.07 mL	115.37 mL	230.73 mL
0.5 mM	4.61 mL	23.07 mL	46.15 mL
1 mM	2.31 mL	11.54 mL	23.07 mL
5 mM	0.46 mL	2.31 mL	4.61 mL

*The above data is based on the productmolecular weight 433.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.