Aripiprazole (Abilify)

Catalog No. A11801

Aripiprazole (Abilify)是人5-HT1A受体部分激动剂，Ki为4.2 nM。

Product Citations

Jaime Osuna-Luque, .et al. Behavioral Mechanisms That Depend on Dopamine and Serotonin in Caenorhabditis elegans Interact With the Antipsychotics Risperidone and Aripiprazole, J Exp Neurosci, 2018, 12: 1179069518798628 PMID: 30245571

Technical details

Catalog Num	A11801
M. Wt	448.39
Formula	C23H27Cl2N3O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	129722-12-9
Synonyms	Abilify
SMILES	C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl

Biological Activity

Aripiprazole (Abilify)是人5-HT1A受体部分激动剂，Ki为4.2 nM。

Targets

5-HT1A
4.2 nM(Ki)

Solubility *

In vitro	DMSO	79 mg/mL (176.18 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.3 mL	111.51 mL	223.02 mL
0.5 mM	4.46 mL	22.3 mL	44.6 mL
1 mM	2.23 mL	11.15 mL	22.3 mL
5 mM	0.45 mL	2.23 mL	4.46 mL

*The above data is based on the productmolecular weight 448.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.