Doxifluridine

Catalog No. A11847

Doxifluridine是PC9-DPE2细胞的胸苷磷酸化酶激活剂，IC50为0.62μM。

Product Citations

Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

Technical details

Catalog Num	A11847
M. Wt	246.19
Formula	C9H11FN2O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	CAS: 3094-09-5
Synonyms	Ro 21-9738, 5-Fluoro-5'-deoxyuridine, 5'-DFUR
SMILES	CC1C(C(C(O1)N2C=C(C(=O)NC2=O)F)O)O

Biological Activity

Doxifluridine是PC9-DPE2细胞的胸苷磷酸化酶激活剂，IC50为0.62μM。

Solubility *

In vitro	DMSO	44 mg/mL (178.72 mM)
	Water	44 mg/mL (178.72 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.62 mL	203.1 mL	406.19 mL
0.5 mM	8.12 mL	40.62 mL	81.24 mL
1 mM	4.06 mL	20.31 mL	40.62 mL
5 mM	0.81 mL	4.06 mL	8.12 mL

*The above data is based on the productmolecular weight 246.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.