Fexofenadine HCl

Catalog No. A11859

Fexofenadine Hydrochloride是一种抗组胺药，可抑制Cox-1，Cox-2，并且是组胺H1受体激动剂，IC50为246 nM。

Technical details

Catalog Num	A11859
M. Wt	538.13
Formula	C32H39NO4.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	153439-40-8
Synonyms	Allegra
SMILES	CC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O.Cl

Biological Activity

Fexofenadine Hydrochloride是一种抗组胺药，可抑制Cox-1，Cox-2，并且是组胺H1受体激动剂，IC50为246 nM。

Targets

Histamine H1 receptor
246 nM

Solubility *

In vitro	DMSO	92 mg/mL (170.97 mM)
	Water	2 mg/mL (3.71 mM)
	Ethanol	92 mg/mL (170.97 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.58 mL	92.91 mL	185.83 mL
0.5 mM	3.72 mL	18.58 mL	37.17 mL
1 mM	1.86 mL	9.29 mL	18.58 mL
5 mM	0.37 mL	1.86 mL	3.72 mL

*The above data is based on the productmolecular weight 538.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.