WIN 55,212-2 mesylate

Catalog No. A11932

WIN 55,212-2 mesylate是一种有效的cannabinoid receptor激动剂，在神经性疼痛的大鼠模型中具有有效的镇痛作用。它通过受体介导的信号激活p42和p44 MAP激酶。

Product Citations

Greish K, .et al. Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer, J Control Release, 2018, Dec 10;291:184-195 PMID: 30367922

Technical details

Catalog Num	A11932
M. Wt	522.6
Formula	C27H26N2O3.CH3SO3H
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	131543-23-2
Synonyms	(R)-(+)-WIN 55212
SMILES	CC1=C(C2=C3N1[C@@H](COC3=CC=C2)CN4CCOCC4)C(=O)C5=CC=CC6=CC=CC=C65.CS(=O)(=O)O

Biological Activity

WIN 55,212-2 mesylate是一种有效的cannabinoid receptor激动剂，在神经性疼痛的大鼠模型中具有有效的镇痛作用。它通过受体介导的信号激活p42和p44 MAP激酶。

Solubility *

In vitro	DMSO	90 mg/mL (172.21 mM)
	Water	90 mg/mL (172.21 mM)
	Ethanol	18 mg/mL (34.43 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.14 mL	95.68 mL	191.35 mL
0.5 mM	3.83 mL	19.14 mL	38.27 mL
1 mM	1.91 mL	9.57 mL	19.14 mL
5 mM	0.38 mL	1.91 mL	3.83 mL

*The above data is based on the productmolecular weight 522.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.