ML 7 hydrochloride

Catalog No. A11936

ML 7 hydrochloride是肌球蛋白轻链激酶（MLCK）的选择性抑制剂。

Product Citations

Praneeth Siripurapu, .et al. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration, J Biol Chem, 2017, Oct 20; 292(42): 17482-17495 PMID: 28864771

Technical details

Catalog Num	A11936
M. Wt	452.7
Formula	C15H17IN2O2S.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	110448-33-4
Synonyms	ML-7 HCl
SMILES	C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl

Biological Activity

ML 7 hydrochloride是肌球蛋白轻链激酶（MLCK）的选择性抑制剂。

Targets

Solubility *

In vitro	DMSO	77 mg/mL (170.07 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.09 mL	110.45 mL	220.9 mL
0.5 mM	4.42 mL	22.09 mL	44.18 mL
1 mM	2.21 mL	11.04 mL	22.09 mL
5 mM	0.44 mL	2.21 mL	4.42 mL

*The above data is based on the productmolecular weight 452.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.