Bafilomycin A1

Catalog No. A11961

Bafilomycin A1通过抑制大鼠肝癌细胞系H-4-II-E细胞中自噬体和溶酶体之间的融合来防止自噬泡的成熟。

Technical details

Catalog Num	A11961
M. Wt	622.84
Formula	C35H58O9
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	88899-55-2
Synonyms
SMILES	C[C@H]1C/C(=C/C=C\[C@@H](C(OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)O)O)OC)/C

Biological Activity

Bafilomycin A1通过抑制大鼠肝癌细胞系H-4-II-E细胞中自噬体和溶酶体之间的融合来防止自噬泡的成熟。

Targets

H+-ATPase
0.44 nM

Solubility *

In vitro	DMSO	6 mg/mL (9.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.06 mL	80.28 mL	160.55 mL
0.5 mM	3.21 mL	16.06 mL	32.11 mL
1 mM	1.61 mL	8.03 mL	16.06 mL
5 mM	0.32 mL	1.61 mL	3.21 mL

*The above data is based on the productmolecular weight 622.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.