Src Inhibitor 1

Catalog No. A12299

Src Inhibitor 1 is a potent and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.

Technical details

Catalog Num	A12299
M. Wt	373.4
Formula	C22H19N3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	179248-59-0
Synonyms	Src Kinase Inhibitor 1; Src-l1
SMILES	COC1=CC2=NC=NC(NC3=CC=C(OC4=CC=CC=C4)C=C3)=C2C=C1OC

Biological Activity

Src Inhibitor 1 is a potent and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.

Solubility *

In vitro	DMSO	8 mg/mL (21.42 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (5.35 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.78 mL	133.9 mL	267.81 mL
0.5 mM	5.36 mL	26.78 mL	53.56 mL
1 mM	2.68 mL	13.39 mL	26.78 mL
5 mM	0.54 mL	2.68 mL	5.36 mL

*The above data is based on the productmolecular weight 373.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Src Inhibitor 1

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions