Ampalex (CX-516)

Catalog No. A12349

Ampalex (CX-516)是ampakine和nootropic，充当ampa受体阳性变构调节剂。

Product Citations

Mariusz Papp, .et al. AMPA receptors mediate the pro-cognitive effects of electrical and optogenetic stimulation of the medial prefrontal cortex in antidepressant non-responsive Wistar?CKyoto rats, J Psychopharmacol, 2020, Dec;34(12):1418-1430 PMID: 33200659
Abigail Benn, .et al. Optogenetic Stimulation of Prefrontal Glutamatergic Neurons Enhances Recognition Memory, J Neurosci, 2016, May 4; 36(18):4930-4939 PMID: 27147648

Technical details

Catalog Num	A12349
M. Wt	241.29
Formula	C14H15N3O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	154235-83-3
Synonyms	CX516, CX 516
SMILES	C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2

Biological Activity

Ampalex (CX-516)是ampakine和nootropic，充当ampa受体阳性变构调节剂。

Solubility *

In vitro	DMSO	41 mg/mL (169.92 mM)
	Water	41 mg/mL (169.92 mM)
	Ethanol	41 mg/mL (169.92 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	41.44 mL	207.22 mL	414.44 mL
0.5 mM	8.29 mL	41.44 mL	82.89 mL
1 mM	4.14 mL	20.72 mL	41.44 mL
5 mM	0.83 mL	4.14 mL	8.29 mL

*The above data is based on the productmolecular weight 241.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.