A 967079
Catalog No. A12353
A 967079是选择性TRPA1通道阻滞剂(人和大鼠TRPA1受体的IC50值分别为67和289 nM)。
- L Jin, .et al. Acrolein but not its metabolite, 3-Hydroxypropylmercapturic acid (3HPMA), activates vascular transient receptor potential Ankyrin-1 (TRPA1): Physiological to toxicological implications, Toxicol Appl Pharmacol, 2021, Jul 13;426:115647 PMID: 34271065
- L. Jin, .et al. Crotonaldehyde-induced vascular relaxation and toxicity: Role of endothelium and transient receptor potential ankyrin-1 (TRPA1), Toxicology and Applied Pharmacology, 2020, 398(1),
| Catalog Num | A12353 |
|---|---|
| M. Wt | 207.24 |
| Formula | C12H14FNO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1170613-55-4 |
| Synonyms | A-967079, A967079 |
| SMILES | CC/C(=N/O)/C(=C/C1=CC=C(C=C1)F)/C |
A 967079是选择性TRPA1通道阻滞剂(人和大鼠TRPA1受体的IC50值分别为67和289 nM)。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 48.25 mL | 241.27 mL | 482.53 mL |
| 0.5 mM | 9.65 mL | 48.25 mL | 96.51 mL |
| 1 mM | 4.83 mL | 24.13 mL | 48.25 mL |
| 5 mM | 0.97 mL | 4.83 mL | 9.65 mL |
*The above data is based on the productmolecular weight 207.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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