AZD-2461

Catalog No. A12393

AZD2461是新型有效的PARP抑制剂，对P-糖蛋白的亲和力较低。

Technical details

Catalog Num	A12393
M. Wt	395.43
Formula	C22H22FN3O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1174043-16-3
Synonyms	AZD2461, AZD 2461
SMILES	COC1CCN(CC1)C(=O)C2=C(C=CC(=C2)CC3=NNC(=O)C4=CC=CC=C43)F

Biological Activity

AZD2461是新型有效的PARP抑制剂，对P-糖蛋白的亲和力较低。

Targets

PARP

Solubility *

In vitro (25°C)	DMSO	73 mg/mL (184.61 mM)
	Water	Insoluble
	Ethanol	29 mg/mL (73.33 mM)
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.29 mL	126.44 mL	252.89 mL
0.5 mM	5.06 mL	25.29 mL	50.58 mL
1 mM	2.53 mL	12.64 mL	25.29 mL
5 mM	0.51 mL	2.53 mL	5.06 mL

*The above data is based on the productmolecular weight 395.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.