Vildagliptin

Catalog No. A12528

Vildagliptin 是一种二肽基肽酶4（CD26）抑制剂。

Product Citations

Cecilia Villegas-Novoa, .et al. Development of a Primary Human Intestinal Epithelium Enriched in L-Cells for Assay of GLP-1 Secretion, Anal Chem, 2022, 94(27):9648-9655 PMID: 35758929

Technical details

Catalog Num	A12528
M. Wt	303.4
Formula	C17H25N3O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	274901-16-5
Synonyms
SMILES	C1C[C@H](N(C1)C(=O)CNC23CC4CC(C2)CC(C4)(C3)O)C#N

Biological Activity

Vildagliptin 是一种二肽基肽酶4（CD26）抑制剂。

Targets

DPP-4
2.3 nM

Solubility *

In vitro (25°C)	DMSO	53 mg/mL (174.68 mM)
	Water	53 mg/mL (174.68 mM)
	Ethanol	53 mg/mL (174.68 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.96 mL	164.8 mL	329.6 mL
0.5 mM	6.59 mL	32.96 mL	65.92 mL
1 mM	3.3 mL	16.48 mL	32.96 mL
5 mM	0.66 mL	3.3 mL	6.59 mL

*The above data is based on the productmolecular weight 303.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.