CHMFL-BTK-01

Catalog No. A12538

CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation.
Catalog Num A12538
M. Wt 647.76
Formula C38H41N5O5
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2095280-64-9
Synonyms
SMILES O=C(NC1=CC=CC(C(C=C2NC3=CC=C(C(N4CCOCC4)=O)C(NC(C=C)=O)=C3)=CN(C)C2=O)=C1C)C5=CC=C(C(C)(C)C)C=C5
CHMFL-BTK-01 (compound 9) is a highly selective irreversible BTK inhibitor, with an IC50 of 7 nM. CHMFL-BTK-01 (compound 9) potently inhibited BTK Y223 auto-phosphorylation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.44 mL 77.19 mL 154.38 mL
0.5 mM 3.09 mL 15.44 mL 30.88 mL
1 mM 1.54 mL 7.72 mL 15.44 mL
5 mM 0.31 mL 1.54 mL 3.09 mL

*The above data is based on the productmolecular weight 647.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.