BETd-260

Catalog No. A12563

BETd-260 is a potent BET degrader based on PROTAC technology, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line.
Catalog Num A12563
M. Wt 798.89
Formula C43H46N10O6
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2093388-62-4
Synonyms BETd260, BETd 260, ZBC 260, ZBC-260, ZBC260
SMILES CCN1N=C(C2CC2)C=C1NC3=NC(C(NCCCCCC4=CC=CC5=C4CN(C6C(NC(CC6)=O)=O)C5=O)=O)=NC7=C3C8=CC(OC)=C(C9=C(C)ON=C9C)C=C8N7
BETd-260 is a potent BET degrader based on PROTAC technology, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.52 mL 62.59 mL 125.17 mL
0.5 mM 2.5 mL 12.52 mL 25.03 mL
1 mM 1.25 mL 6.26 mL 12.52 mL
5 mM 0.25 mL 1.25 mL 2.5 mL

*The above data is based on the productmolecular weight 798.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.