EHT 5372
Catalog No. A12586
EHT 5372 is a strong inhibitor of DYRK??s family kinases, with IC50s of 0.22, 0.28 nM for DYRK1A and DYRK1B, respectively.
| Catalog Num | A12586 |
|---|---|
| M. Wt | 383.4 |
| Formula | C18H14FN5O2S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1425945-60-3 |
| Synonyms | EHT-5372, EHT5372 |
| SMILES | N=C(C(S1)=NC2=C1C3=C(NC4=CC=C(OC)C=C4F)N=CN=C3C=C2)OC |
EHT 5372 is a strong inhibitor of DYRK??s family kinases, with IC50s of 0.22, 0.28 nM for DYRK1A and DYRK1B, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.08 mL | 130.41 mL | 260.82 mL |
| 0.5 mM | 5.22 mL | 26.08 mL | 52.16 mL |
| 1 mM | 2.61 mL | 13.04 mL | 26.08 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.22 mL |
*The above data is based on the productmolecular weight 383.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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