WZ811

Catalog No. A12588

WZ811是4型C-X-C趋化因子受体（CXCR4）拮抗剂（EC50 = 0.3 nM）。在体外抑制CXCR4/基质细胞衍生因子1（SDF-1）介导的cAMP调节（EC50 = 1.2 nM）。

Technical details

Catalog Num	A12588
M. Wt	290.36
Formula	C18H18N4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	55778-02-4
Synonyms	WZ811; WZ-811; WZ 811.
SMILES	C1=CC=NC(=C1)NCC2=CC=C(C=C2)CNC3=CC=CC=N3

Biological Activity

WZ811是4型C-X-C趋化因子受体（CXCR4）拮抗剂（EC50 = 0.3 nM）。在体外抑制CXCR4/基质细胞衍生因子1（SDF-1）介导的cAMP调节（EC50 = 1.2 nM）。

Targets

CXCR4
0.3 nM(EC50)

Solubility *

In vitro	DMSO	29 mg/mL (99.88 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	34.44 mL	172.2 mL	344.4 mL
0.5 mM	6.89 mL	34.44 mL	68.88 mL
1 mM	3.44 mL	17.22 mL	34.44 mL
5 mM	0.69 mL	3.44 mL	6.89 mL

*The above data is based on the productmolecular weight 290.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.