Ascomycin

Catalog No. A12592

Ascomycin是一种有效的免疫抑制剂，可用作自身免疫性疾病的潜在治疗剂。

Technical details

Catalog Num	A12592
M. Wt	792.01
Formula	C43H69NO12
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	104987-12-4
Synonyms	FK 520, FR 900520, FK520, FR900520
SMILES	CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)\C

Biological Activity

Ascomycin是一种有效的免疫抑制剂，可用作自身免疫性疾病的潜在治疗剂。

Targets

calcineurin phosphatase
49 nM

Solubility *

In vitro	DMSO	98 mg/mL (123.73 mM)
	Water	Insoluble
	Ethanol	98 mg/mL (123.73 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.63 mL	63.13 mL	126.26 mL
0.5 mM	2.53 mL	12.63 mL	25.25 mL
1 mM	1.26 mL	6.31 mL	12.63 mL
5 mM	0.25 mL	1.26 mL	2.53 mL

*The above data is based on the productmolecular weight 792.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.