MSC2530818

Catalog No. A12644

MSC2530818 is a potent, selective and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8.
Catalog Num A12644
M. Wt 340.81
Formula C18H17ClN4O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1883423-59-3
Synonyms MSC-2530818; MSC 2530818
SMILES O=C(N1[C@H](C2=CC=C(Cl)C=C2)CCC1)C3=CN=C(NN=C4C)C4=C3
MSC2530818 is a potent, selective and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8.
In vitro DMSO 66 mg/mL (193.65 mM)
Water Insoluble
Ethanol 66 mg/mL (193.65 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.34 mL 146.71 mL 293.42 mL
0.5 mM 5.87 mL 29.34 mL 58.68 mL
1 mM 2.93 mL 14.67 mL 29.34 mL
5 mM 0.59 mL 2.93 mL 5.87 mL

*The above data is based on the productmolecular weight 340.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.