LX-4211

Catalog No. A12680

LX4211是双重SGLT1/SGLT2抑制剂。

Technical details

Catalog Num	A12680
M. Wt	424.94
Formula	C21H25ClO5S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1018899-04-1
Synonyms	LX4211, LX4211
SMILES	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)SC)O)O)O)Cl

Biological Activity

LX4211是双重SGLT1/SGLT2抑制剂。

Targets

SGLT2	SGLT1
1.8 nM	36 nM

Solubility *

In vitro (25°C)	DMSO	72 mg/mL (169.43 mM)
	Water	Insoluble
	Ethanol	Warmed: 15 mg/mL (35.29 mM)
In vivo	5% DMSO+45% PEG 300+ddH2O	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.53 mL	117.66 mL	235.33 mL
0.5 mM	4.71 mL	23.53 mL	47.07 mL
1 mM	2.35 mL	11.77 mL	23.53 mL
5 mM	0.47 mL	2.35 mL	4.71 mL

*The above data is based on the productmolecular weight 424.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.