LDN-57444
Catalog No. A12715
LDN-57444是UCHL1的有效,可逆,竞争和活性定点抑制剂。
Catalog Num | A12715 |
---|---|
M. Wt | 397.64 |
Formula | C17H11Cl3N2O3 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 668467-91-2 |
Synonyms | C30, LDN 57444, LDN57444 |
SMILES | CC(=O)O/N=C/1\C2=C(C=CC(=C2)Cl)N(C1=O)CC3=C(C=CC(=C3)Cl)Cl |
LDN-57444是UCHL1的有效,可逆,竞争和活性定点抑制剂。
Targets
UCH-L1 | UCH-L1 | UCH-L3 | ||
0.4 μM(Ki) | 0.88 μM | 25 μM |
In vitro (25°C) | DMSO | 11 mg/mL (27.66 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+corn oil | 5 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.15 mL | 125.74 mL | 251.48 mL |
0.5 mM | 5.03 mL | 25.15 mL | 50.3 mL |
1 mM | 2.51 mL | 12.57 mL | 25.15 mL |
5 mM | 0.5 mL | 2.51 mL | 5.03 mL |
*The above data is based on the productmolecular weight 397.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.