Tirapazamine

Catalog No. A12754

Tirapazamine是一种生物还原，抗肿瘤，抗癌剂，在缺氧条件下对细胞有选择性毒性。

Product Citations

Zhu R, .et al. Cancer-selective bioreductive chemotherapy mediated by dual hypoxia-responsive nanomedicine upon photodynamic therapy-induced hypoxia aggravation, Biomacromolecules, 2019, May 24 PMID: 31125209

Technical details

Catalog Num	A12754
M. Wt	178.15
Formula	C7H6N4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	27314-97-2
Synonyms
SMILES	C1=CC=C2C(=C1)N(C(=N)N=[N+]2[O-])O

Biological Activity

Tirapazamine是一种生物还原，抗肿瘤，抗癌剂，在缺氧条件下对细胞有选择性毒性。

Solubility *

In vitro	DMSO	32 mg/mL (179.62 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	56.13 mL	280.66 mL	561.32 mL
0.5 mM	11.23 mL	56.13 mL	112.26 mL
1 mM	5.61 mL	28.07 mL	56.13 mL
5 mM	1.12 mL	5.61 mL	11.23 mL

*The above data is based on the productmolecular weight 178.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.