Freselestat (ONO-6818)
Catalog No. A12780
Freselestat是一种有效的嗜中性粒细胞弹性蛋白酶抑制剂。 在模拟体外循环过程中，Freselestat减少了炎症介质。 ONO-6818显着降低了白介素8和C5b-9的产量。 在再循环期间，ONO-6818不能调节CD11b和L-选择素的变化。
| Catalog Num | A12780 |
|---|---|
| M. Wt | 452.51 |
| Formula | C23H28N6O4 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 208848-19-5 |
| Synonyms | ONO6818, ONO 6818 |
| SMILES | C3=C(C1=NC=C(C(N1CC(NC(C(C2=NN=C(O2)C(C)(C)C)=O)C(C)C)=O)=O)N)C=CC=C3 |
Freselestat是一种有效的嗜中性粒细胞弹性蛋白酶抑制剂。 在模拟体外循环过程中，Freselestat减少了炎症介质。 ONO-6818显着降低了白介素8和C5b-9的产量。 在再循环期间，ONO-6818不能调节CD11b和L-选择素的变化。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.1 mL | 110.49 mL | 220.99 mL |
| 0.5 mM | 4.42 mL | 22.1 mL | 44.2 mL |
| 1 mM | 2.21 mL | 11.05 mL | 22.1 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.42 mL |
*The above data is based on the productmolecular weight 452.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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