LDN-212854

Catalog No. A12821

LDN-212854是一种ALK2偏爱的BMP I型受体激酶抑制剂。

Technical details

Catalog Num	A12821
M. Wt	406.5
Formula	C25H22N6
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1432597-26-6
Synonyms	LDN212854, LDN 212854
SMILES	C12=C(C3=C4N=CC(C5=CC=C(N6CCNCC6)C=C5)=CN4N=C3)C=CC=C1N=CC=C2

Biological Activity

LDN-212854是一种ALK2偏爱的BMP I型受体激酶抑制剂。

Targets

ALK2	ALK1	ALK3	ALK4	ALK5
1.3 nM	2.4 nM	85.8 nM	2133 nM	9276 nM

Solubility *

In vitro	DMSO	Warmed: 73 mg/mL (179.59 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.6 mL	123 mL	246 mL
0.5 mM	4.92 mL	24.6 mL	49.2 mL
1 mM	2.46 mL	12.3 mL	24.6 mL
5 mM	0.49 mL	2.46 mL	4.92 mL

*The above data is based on the productmolecular weight 406.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.