MI 2

Catalog No. A12928

MI 2直接与MALT1结合并在体外和体内抑制活化的B细胞样弥漫性大B细胞淋巴瘤（ABC-DLBCL）。

Technical details

Catalog Num	A12928
M. Wt	455.72
Formula	C19H17Cl3N4O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1047953-91-2
Synonyms	MALT1 inhibitor, MI-2
SMILES	COCCOC1=NN(C(=N1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)NC(=O)CCl

Biological Activity

MI 2直接与MALT1结合并在体外和体内抑制活化的B细胞样弥漫性大B细胞淋巴瘤（ABC-DLBCL）。

Targets

MALT1
5.84 μM

Solubility *

In vitro (25°C)	DMSO	77 mg/mL (168.96 mM)
	Water	Insoluble
	Ethanol	77 mg/mL (168.96 mM)
In vivo	5%DMSO+30%PEG300+5%Tween-80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.94 mL	109.72 mL	219.43 mL
0.5 mM	4.39 mL	21.94 mL	43.89 mL
1 mM	2.19 mL	10.97 mL	21.94 mL
5 mM	0.44 mL	2.19 mL	4.39 mL

*The above data is based on the productmolecular weight 455.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.