Ingenol Mebutate (PEP005)

Catalog No. A12963

Ingenol Mebutate (PEP005)是一种存在于植物大戟汁液中的物质,是细胞死亡的诱导剂。
  • Yao-Yu Hsieh, .et al. Repurposing of ingenol mebutate for treating human colorectal cancer by targeting S100 calcium-binding protein A4 (S100A4), Toxicol Appl Pharmacol, 2022, Aug 15;449 PMID: 35724704
Catalog Num A12963
M. Wt 430.53
Formula C25H34O6
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 75567-37-2
Synonyms PEP005, PEP-005, PEP 005, ingenol-3-angelate, I3A
SMILES C/C=C(C)\C(O[C@H]1C(C)=CC23[C@]1(O)[C@H](O)C(CO)=CC(C3=O)[C@]4([H])C(C4(C)C)C[C@H]2C)=O
Ingenol Mebutate (PEP005)是一种存在于植物大戟汁液中的物质,是细胞死亡的诱导剂。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.23 mL 116.14 mL 232.27 mL
0.5 mM 4.65 mL 23.23 mL 46.45 mL
1 mM 2.32 mL 11.61 mL 23.23 mL
5 mM 0.46 mL 2.32 mL 4.65 mL

*The above data is based on the productmolecular weight 430.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.