Lesinurad

Catalog No. A12981

Lesinurad是一种选择性的尿酸重吸收抑制剂（SURI），也是URAT1的一种选择性抑制剂，URAT1是肾脏中调节人体尿酸排泄的转运蛋白。

Technical details

Catalog Num	A12981
M. Wt	404.28
Formula	C17H14BrN3O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	878672-00-5
Synonyms	RDEA594, RDEA 594, RDEA-594
SMILES	C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)O

Biological Activity

Lesinurad是一种选择性的尿酸重吸收抑制剂（SURI），也是URAT1的一种选择性抑制剂，URAT1是肾脏中调节人体尿酸排泄的转运蛋白。

Targets

URAT1

Solubility *

In vitro	DMSO	72 mg/mL (178.09 mM)
	Water	Insoluble
	Ethanol	49 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.74 mL	123.68 mL	247.35 mL
0.5 mM	4.95 mL	24.74 mL	49.47 mL
1 mM	2.47 mL	12.37 mL	24.74 mL
5 mM	0.49 mL	2.47 mL	4.95 mL

*The above data is based on the productmolecular weight 404.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.