INCB024360 analog

Catalog No. A13004

INCB024360 analog是一种羟胺和吲哚胺2,3-二加氧酶(IDO1)抑制剂,具有潜在的免疫调节和抗肿瘤活性。
Catalog Num A13004
M. Wt 271.63
Formula C9H7ClFN5O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 914471-09-3
Synonyms INCB-024360, INCB 024360
SMILES C1=CC(=C(C=C1N/C(=C\2/C(=NON2)N)/N=O)Cl)F
INCB024360 analog是一种羟胺和吲哚胺2,3-二加氧酶(IDO1)抑制剂,具有潜在的免疫调节和抗肿瘤活性。
Targets
IDO1
67 nM
In vitro (25°C) DMSO Warmed: 46 mg/mL (169.34 mM)
Water Insoluble
Ethanol Warmed: 46 mg/mL (169.34 mM)
In vivo 5% DMSO+45% PEG 300+ddH2O 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.81 mL 184.07 mL 368.15 mL
0.5 mM 7.36 mL 36.81 mL 73.63 mL
1 mM 3.68 mL 18.41 mL 36.81 mL
5 mM 0.74 mL 3.68 mL 7.36 mL

*The above data is based on the productmolecular weight 271.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.