mTOR inhibitor-2
Catalog No. A13035
mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates.
Catalog Num | A13035 |
---|---|
M. Wt | 411.46 |
Formula | C23H21N7O |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 2219323-96-1 |
Synonyms | |
SMILES | O=C(N1C2CCN(CC#N)CC2)C=NC3=C1C4=CC(C5=CN=C(N)C=C5)=CC=C4N=C3 |
mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.3 mL | 121.52 mL | 243.04 mL |
0.5 mM | 4.86 mL | 24.3 mL | 48.61 mL |
1 mM | 2.43 mL | 12.15 mL | 24.3 mL |
5 mM | 0.49 mL | 2.43 mL | 4.86 mL |
*The above data is based on the productmolecular weight 411.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.