AZ505

Catalog No. A13061

AZ505是一种有效且高度选择性的致癌蛋白SMYD2抑制剂(IC50 = 0.12μM),具有潜在的抗癌活性,是SMYD3(IC50> 83.3μM)的600倍以上; DOT1L(IC50> 83.3μM); EZH2(IC50> 83.3μM)。
Catalog Num A13061
M. Wt 577.54
Formula C29H38Cl2N4O4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1035227-43-0
Synonyms AZ 505, AZ-505
SMILES C1CCC(CC1)N(CCNCCC2=C3C(=C(C=C2)O)NC(=O)CO3)C(=O)CCNCCC4=CC(=C(C=C4)Cl)Cl
AZ505是一种有效且高度选择性的致癌蛋白SMYD2抑制剂(IC50 = 0.12μM),具有潜在的抗癌活性,是SMYD3(IC50> 83.3μM)的600倍以上; DOT1L(IC50> 83.3μM); EZH2(IC50> 83.3μM)。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.31 mL 86.57 mL 173.15 mL
0.5 mM 3.46 mL 17.31 mL 34.63 mL
1 mM 1.73 mL 8.66 mL 17.31 mL
5 mM 0.35 mL 1.73 mL 3.46 mL

*The above data is based on the productmolecular weight 577.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.