AZ505
Catalog No. A13061
AZ505是一种有效且高度选择性的致癌蛋白SMYD2抑制剂(IC50 = 0.12μM),具有潜在的抗癌活性,是SMYD3(IC50> 83.3μM)的600倍以上; DOT1L(IC50> 83.3μM); EZH2(IC50> 83.3μM)。
Catalog Num | A13061 |
---|---|
M. Wt | 577.54 |
Formula | C29H38Cl2N4O4 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1035227-43-0 |
Synonyms | AZ 505, AZ-505 |
SMILES | C1CCC(CC1)N(CCNCCC2=C3C(=C(C=C2)O)NC(=O)CO3)C(=O)CCNCCC4=CC(=C(C=C4)Cl)Cl |
AZ505是一种有效且高度选择性的致癌蛋白SMYD2抑制剂(IC50 = 0.12μM),具有潜在的抗癌活性,是SMYD3(IC50> 83.3μM)的600倍以上; DOT1L(IC50> 83.3μM); EZH2(IC50> 83.3μM)。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.31 mL | 86.57 mL | 173.15 mL |
0.5 mM | 3.46 mL | 17.31 mL | 34.63 mL |
1 mM | 1.73 mL | 8.66 mL | 17.31 mL |
5 mM | 0.35 mL | 1.73 mL | 3.46 mL |
*The above data is based on the productmolecular weight 577.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.