NS-398

Catalog No. A13116

NS-398是具有镇痛和解热作用的非甾体类抗炎药，可选择性抑制前列腺素G / H合酶2 /环氧合酶2（COX-2）活性，IC50为3.8μM，对COX无影响

Technical details

Catalog Num	A13116
M. Wt	314.36
Formula	C13H18N2O5S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	123653-11-2
Synonyms	NS398, NS 398
SMILES	CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2

Biological Activity

NS-398是具有镇痛和解热作用的非甾体类抗炎药，可选择性抑制前列腺素G / H合酶2 /环氧合酶2（COX-2）活性，IC50为3.8μM，对COX无影响

Targets

Solubility *

In vitro	DMSO	53 mg/mL (168.59 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.81 mL	159.05 mL	318.11 mL
0.5 mM	6.36 mL	31.81 mL	63.62 mL
1 mM	3.18 mL	15.91 mL	31.81 mL
5 mM	0.64 mL	3.18 mL	6.36 mL

*The above data is based on the productmolecular weight 314.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.