AZD1981

Catalog No. A13186

AZD1981作为疾病相关细胞系统的有效拮抗剂，可抑制DK-PGD2诱导的人嗜酸性粒细胞CD11b表达，IC50为10 nM。

Technical details

Catalog Num	A13186
M. Wt	388.87
Formula	C19H17ClN2O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	802904-66-1
Synonyms	AZD-1981, AZD 1981
SMILES	CC1=C(C2=C(N1CC(=O)O)C=CC=C2NC(=O)C)SC3=CC=C(C=C3)Cl

Biological Activity

AZD1981作为疾病相关细胞系统的有效拮抗剂，可抑制DK-PGD2诱导的人嗜酸性粒细胞CD11b表达，IC50为10 nM。

Targets

CRTh2 (DP2) receptor
4 nM

Solubility *

In vitro	DMSO	9 mg/mL (23.14 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.72 mL	128.58 mL	257.16 mL
0.5 mM	5.14 mL	25.72 mL	51.43 mL
1 mM	2.57 mL	12.86 mL	25.72 mL
5 mM	0.51 mL	2.57 mL	5.14 mL

*The above data is based on the productmolecular weight 388.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.