AZ-20

Catalog No. A13205

AZ20是一种有效的选择性ATR抑制剂，IC50值为5 nM。

Technical details

Catalog Num	A13205
M. Wt	412.51
Formula	C21H24N4O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1233339-22-4
Synonyms	AZ20, AZ 20
SMILES	C[C@@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=O)(=O)C)C4=C5C=CNC5=CC=C4

Biological Activity

AZ20是一种有效的选择性ATR抑制剂，IC50值为5 nM。

Targets

ATR (Cell-free assay)	mTOR (Cell-free assay)
5 nM	38 nM

Solubility *

In vitro	DMSO	80 mg/mL (193.93 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (7.27 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.24 mL	121.21 mL	242.42 mL
0.5 mM	4.85 mL	24.24 mL	48.48 mL
1 mM	2.42 mL	12.12 mL	24.24 mL
5 mM	0.48 mL	2.42 mL	4.85 mL

*The above data is based on the productmolecular weight 412.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.