RO3280

Catalog No. A13245

RO3280是一种有效的,高选择性的Polo样激酶1(PLK1)抑制剂,IC50为3 nM。
Catalog Num A13245
M. Wt 543.61
Formula C27H35F2N7O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1062243-51-9
Synonyms RO 3280, RO-3280
SMILES CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC
RO3280是一种有效的,高选择性的Polo样激酶1(PLK1)抑制剂,IC50为3 nM。
In vitro DMSO 87 mg/mL (160.04 mM)
Water Insoluble
Ethanol 87 mg/mL (160.04 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.98 mL 183.96 mL
0.5 mM 3.68 mL 18.4 mL 36.79 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.