Fidaxomicin

Catalog No. A13271

Fidaxomicin是大环内酯家族的主要类似物，该大环内酯家族分别从三个不同属（猕猴桃属，Dactylosporangium和微单孢菌属）的三个不同组别分离，分别被称为利比霉素A3，头孢菌素B和梭菌素B1。非达霉素是一种窄谱抗生素，对革兰氏阳性细菌特别是艰难梭菌具有极好的活性。非达霉素在胃肠道中起作用而不会过度破坏肠道微生物菌群。

Technical details

Catalog Num	A13271
M. Wt	1058.04
Formula	C52H74Cl2O18
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	873857-62-6
Synonyms
SMILES	CC[C@H]1/C=C(\[C@H](C/C=C/C=C(/C(=O)O[C@@H](C/C=C(/C=C(/C1O[C@H]2[C@H]([C@H]([C@@H](C(O2)(C)C)OC(=O)C(C)C)O)O)\C)\C)[C@@H](C)O)\CO[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)OC(=O)C4=C(C(=C(C(=C4O)Cl)O)Cl)CC)O)OC)O)/C

Biological Activity

Targets

RNA polymerase

Solubility *

In vitro	DMSO	92 mg/mL (86.95 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	9.45 mL	47.26 mL	94.51 mL
0.5 mM	1.89 mL	9.45 mL	18.9 mL
1 mM	0.95 mL	4.73 mL	9.45 mL
5 mM	0.19 mL	0.95 mL	1.89 mL

*The above data is based on the productmolecular weight 1058.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.