HC-030031

Catalog No. A13278

HC-030031是选择性TRPA1阻滞剂，可拮抗AITC和福尔马林诱导的TRPA1介导的钙内流（IC50分别为6.2和5.3 uM）。

Technical details

Catalog Num	A13278
M. Wt	355.4
Formula	C18H21N5O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	349085-38-7
Synonyms	HC030031
SMILES	CC(C)C1=CC=C(C=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C

Biological Activity

HC-030031是选择性TRPA1阻滞剂，可拮抗AITC和福尔马林诱导的TRPA1介导的钙内流（IC50分别为6.2和5.3 uM）。

Targets

TRPA1

Solubility *

In vitro (25°C)	DMSO	27 mg/mL (75.97 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.14 mL	140.69 mL	281.37 mL
0.5 mM	5.63 mL	28.14 mL	56.27 mL
1 mM	2.81 mL	14.07 mL	28.14 mL
5 mM	0.56 mL	2.81 mL	5.63 mL

*The above data is based on the productmolecular weight 355.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.