GSK-650394

Catalog No. A13309

GSK 650394是一种糖皮质激素和血清调节激酶1（SGK1）抑制剂，对LNCaP前列腺癌细胞系表现出抗增殖特性。

Technical details

Catalog Num	A13309
M. Wt	382.45
Formula	C25H22N2O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	890842-28-1
Synonyms	GSK 650394, GSK650394
SMILES	C1CCC(C1)C2=C(C=CC(=C2)C3=CNC4=NC=C(C=C34)C5=CC=CC=C5)C(=O)O

Biological Activity

GSK 650394是一种糖皮质激素和血清调节激酶1（SGK1）抑制剂，对LNCaP前列腺癌细胞系表现出抗增殖特性。

Targets

SGK1	SGK2
62 nM	103 nM

Solubility *

In vitro	DMSO	72 mg/mL (188.25 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.15 mL	130.74 mL	261.47 mL
0.5 mM	5.23 mL	26.15 mL	52.29 mL
1 mM	2.61 mL	13.07 mL	26.15 mL
5 mM	0.52 mL	2.61 mL	5.23 mL

*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.